48 Hours in San Francisco: Your Guide to the City by the Bay

Golden Gate Bridge in San Francisco during a California trip

If you’re lucky enough to find yourself with 48 hours in San Francisco, and unlucky enough to have no clue where to start to explore the countless sights—read on.

The City by the Bay is famous for its fog (affectionately known as Karl), its cable cars, steep hills, Ghirardelli chocolate, and of course—the infamous Golden Gate Bridge.

Two days may not be enough to experience everything San Francisco has to offer, but it’s definitely enough time to get a taste of what makes this California city so special. And if you’re still figuring out what to bring, my travel packing tips can help you pack for those unpredictable San Francisco temperatures.

Grab your walking shoes—and maybe a jacket—and let’s explore San Francisco!

Day 1: See the San Francisco Classics

With only 48 hours in the city, your first day is all about experiencing some of the places San Francisco is famous for.

And we’re starting with the big one.

Golden Gate Bridge

48 hours in San Francisco at the Golden Gate Bridge

Can you really say you’ve been to San Francisco without seeing the Golden Gate Bridge?

Probably. But why would you? Seeing the bridge in person is completely different from seeing it in pictures. Give yourself enough time to actually enjoy the views instead of treating it like a five-minute photo stop.

Also remember: San Francisco’s weather has a personality of its own.

You might arrive expecting a perfectly clear view and find Karl the Fog waiting for you instead. Don’t let that ruin the experience. The fog is practically a local celebrity.

I was lucky enough to get a pretty clear view when I visited, and naturally I had to get a picture. Some landmarks are famous for a reason, and this is definitely one of them.

Visit the Painted Ladies

Brittney visiting the Painted Ladies in San Francisco

Next, make your way to another one of those instantly recognizable San Francisco sights: the Painted Ladies.

If you grew up watching Full House, there’s a good chance these colorful Victorian houses already feel strangely familiar. Seeing them with the San Francisco skyline in the background is one of those classic city views that’s worth making time for.

You don’t need hours here. Walk around, take some pictures, enjoy the park and then keep exploring.

Find the Mrs. Doubtfire House

Visiting the Mrs. Doubtfire house in San Francisco

Apparently my San Francisco sightseeing itinerary was heavily influenced by movies and television, because I also had to see the house from Mrs. Doubtfire. I regret nothing.

Sometimes travel isn’t about finding the most obscure attraction nobody else knows about. Sometimes it’s standing outside a house you recognize from a movie you’ve watched a hundred times and thinking: Yep. This is cool.

Those little moments are part of the fun.

Explore Fisherman’s Wharf

Next, make your way toward Fisherman’s Wharf. Yes, it’s touristy. You’re also a tourist. Embrace it.

The waterfront area is full of restaurants, shops, attractions and plenty of people doing exactly what you’re doing—trying to experience as much of San Francisco as possible.

Walk around, enjoy the waterfront and give yourself some time to explore instead of racing to the next attraction.

Check Out Pier 39

Enjoy the sea lions sunbathing on Pier39 in San Francisco

While you’re in the Fisherman’s Wharf area, head toward Pier 39.

Walk around the pier, check out the shops, enjoy the waterfront views and see what’s happening.

And keep an eye—or an ear—out for the sea lions. They’re not exactly known for being subtle.

Grab Some Ghirardelli Chocolate

You knew this was coming. You’re in San Francisco. There is chocolate. We need to investigate.

Make your way toward Ghirardelli Square and treat yourself to something sweet.

Vacation calories don’t count…

Okay, they absolutely do. But that’s a problem for Future You. Current You is in San Francisco. Eat the chocolate.

Ride a Cable Car

People taking a cable car on the streets of San Francisco

Few things scream San Francisco quite like a cable car climbing one of the city’s ridiculously steep hills.

It’s touristy. It’s iconic. And if this is your first trip to the city, it’s worth experiencing at least once.

A cable-car ride also gives your legs a temporary break from San Francisco’s hills, which they’ll probably appreciate by this point.

Because those hills? They are not playing around.

I learned very quickly in San Francisco that I was apparently not in nearly as good of shape as I thought I was. LOL I spent a lot of time walking uphill and wondering why breathing had suddenly become so difficult.

San Francisco will humble you.

End Day 1 With Dinner, Drinks and a San Francisco Sunset

After a full day of sightseeing, slow down.

You’ve already covered some of San Francisco’s biggest sights. You do not need to squeeze another six attractions into the final two hours of your day.

One of my food stops during my trip was MAC’D, a build-your-own macaroni and cheese spot where you could basically create your dream bowl of comfort food. Sadly, the San Francisco location has since permanently closed, but I’m still glad I got to try it while it was around. And yes, I have photographic evidence of the mac and cheese because apparently this was an important moment in my life. LOL

Macaroni and cheese from the former MAC'D restaurant in San Francisco

I also ended up having drinks at a tiki bar, which was a fun change of pace after a full day of sightseeing. Find somewhere interesting for dinner or drinks, enjoy the evening and give your feet a break.

You’re going to need them again tomorrow.

Day 2: Neighborhoods, Food & More Exploring

Day 1 gave you the postcard version of San Francisco. For Day 2, slow things down a little and experience more of the city itself.

Explore Chinatown

Start your second day in Chinatown.

San Francisco’s Chinatown is one of the city’s most historic and recognizable neighborhoods, and it’s an area worth experiencing rather than simply walking through on your way somewhere else.

Give yourself time to wander. Check out the shops. Look at the architecture. But most importantly: Come hungry. This is not the morning to eat an enormous hotel breakfast. Save some room.

Travel and food belong together.

Give Yourself Time to Wander

Here’s something I would intentionally build into a 48-hour San Francisco itinerary: Time to wander. Not every minute needs a reservation.

San Francisco is the kind of city where you can turn a corner and suddenly find an interesting street, beautiful building, café, shop or view you didn’t know existed. Give yourself permission to deviate from the itinerary.

You only have 48 hours, but that doesn’t mean you need to experience them at maximum speed.

Find Those Classic San Francisco Views

San Francisco’s hills may make your legs question your life choices, but they also create some incredible views. As you’re exploring, stop and look around.

The combination of hills, colorful buildings, water, bridges, cable cars and fog gives San Francisco a visual identity unlike almost anywhere else.

This is one of those cities where getting from one attraction to another can become part of the sightseeing.

Assuming you survive the hill.

Eat Something Memorable

In-N-Out Burger meal during a San Francisco trip

San Francisco is a fantastic food city, so don’t let your entire culinary experience consist of whatever happens to be closest to the tourist attractions.

Try something different. Ask for recommendations. Explore neighborhood restaurants. Grab something in Chinatown. Have seafood near the waterfront if that’s your thing. I also made an In-N-Out stop while I was in California. It may not be uniquely San Francisco, but when you’re visiting from the East Coast, sometimes trying the West Coast fast-food institution is part of the experience.

And obviously we’ve already established that chocolate is a requirement. You have only 48 hours. Make those meals count.

Leave Room for Something You Didn’t Plan

By your second afternoon, resist the urge to cram every remaining San Francisco attraction onto a checklist.

Maybe you discover a neighborhood you want to explore longer. Maybe somebody recommends a restaurant. Maybe you find a bar that looks fun. Maybe the weather is finally perfect and you decide you’d rather sit somewhere with a great view than rush across town. Do that.

Some of my favorite travel memories have come from things I didn’t plan before the trip. An itinerary should help you experience a destination.

It shouldn’t hold you hostage.

A Few Things to Know Before Visiting San Francisco

Before you start packing, there are a couple of things San Francisco would probably like you to know.

Dress in Layers

California does not automatically mean hot.

San Francisco can be surprisingly cool, windy and foggy—even when another part of California is experiencing completely different weather.

A sunny afternoon can turn chilly quickly, so having a light jacket or sweater with you can save you from buying an emergency San Francisco sweatshirt that says:

I underestimated Karl the Fog and all I got was this overpriced hoodie.

Although, honestly, that’s a pretty good souvenir.

Don’t Underestimate the Hills

I cannot emphasize this enough. ♫ The hills are alive with the sound of…gasping for air ♫ LOL

San Francisco is walkable in the sense that you can walk around it. Whether your legs will agree with that definition is another matter.

Wear comfortable shoes. Wearing the wrong shoes is one of those common travel mistakes that can become painfully obvious in a city this hilly. This is not the trip for breaking in brand-new footwear. Use public transportation when it makes sense, take breaks and don’t feel like you have to walk absolutely everywhere just to prove something. Your vacation is not an endurance competition.

And if you find yourself halfway up a hill pretending you stopped because you wanted to admire the architecture rather than because you desperately need to catch your breath…

I understand.

Don’t Try to See Everything

This might be the most important part of planning a short city break.

You cannot see all of San Francisco in 48 hours and you don’t need to.

Choose the experiences that interest you most and give yourself enough time to actually enjoy them. A trip filled with eight memorable experiences is better than one filled with 27 blurry attractions you barely remember because you were constantly checking the time.

Is 48 Hours in San Francisco Enough?

Enough to see everything? Absolutely not.

Enough to have a fantastic introduction to the city? Definitely.

In two days, you can see the Golden Gate Bridge, visit the Painted Ladies, explore Fisherman’s Wharf and Chinatown, ride a cable car, grab some Ghirardelli chocolate, battle the hills, meet Karl the Fog and still leave knowing there’s much more waiting for you and that’s not necessarily a bad thing.

A good destination should leave you wanting more. If you only have 48 hours in San Francisco, the key is choosing a mix of iconic sights and time to simply enjoy the city.

Your 48-Hour San Francisco Itinerary at a Glance

Day 1:
Golden Gate Bridge → Painted Ladies → Mrs. Doubtfire house → Fisherman’s Wharf → Pier 39 → Ghirardelli Square → cable car → dinner, drinks and sunset

Day 2:
Chinatown → neighborhood exploring → memorable food → wandering → city views → one last San Francisco adventure

Don’t worry about seeing everything. You can’t. Instead, focus on experiencing the city.

Take pictures. Eat something good. Walk down streets that look interesting. Ride the cable car. Laugh when the fog ruins the perfect Golden Gate Bridge photo you had planned.

That’s travel.

And after 48 hours in the City by the Bay, don’t be surprised if you’re already planning a return trip. San Francisco also made my list of favorite girls’ trip destinations if you’re planning a city getaway with friends.